Enhancing resilience for young children facing toxic stress

When a child is confronted with severe, long-lasting stressors and is not buffered from these negative circumstances by a caring and capable adult, their body's stress response system is compromised, leading to what is referred to as "toxic stress." These negative experiences early in a child's life lead to difficulties in learning, behavior, and overall physical and mental health. These challenges can be both short and long term, with potentially devastating effects on the child's ability to develop relationships, perform well in school and in the workplace, and choose healthy lifestyle habits that support physical and mental well-being. Millions of children in America, with children of color disproportionately represented, were battling toxic stress before the COVID-19 pandemic, and it is still unknown the extent to which the pandemic will exacerbate these risk factors. While it is difficult to maintain hope and optimism in the face of such overwhelming adversity, the science of resilience does help justify this position. Decades of resilience research demonstrate that key protective factors can be cultivated to support children and families to successfully confront adversity and achieve positive outcomes. These protective factors are found externally within the environment and the family as well as within the individual. This chapter will focus on those protective factors that are drawn from within children, including skills and behaviors that are strengthened through healthy relationships with parents and other important adult caregivers. Practical applications for strengthening children's within-child protective factors will be discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

Implementation Evaluation of HUGS/Abrazos During the COVID-19 Pandemic: A Program to Foster Resiliency in Pregnancy and Early Childhood.

Early life adversity can significantly impact child development and health outcomes throughout the life course. With the COVID-19 pandemic exacerbating preexisting and introducing new sources of toxic stress, social programs that foster resilience are more necessary now than ever. The Helping Us Grow Stronger (HUGS/Abrazos) program fills a crucial need for protective buffers during the COVID-19 pandemic, which has escalated toxic stressors affecting pregnant women and families with young children. HUGS/Abrazos combines patient navigation, behavioral health support, and innovative tools to ameliorate these heightened toxic stressors. We used a mixed-methods approach, guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework, to evaluate the implementation of the HUGS/Abrazos program at Massachusetts General Hospital from 6/30/2020-8/31/2021. Results of the quality improvement evaluation revealed that the program was widely adopted across the hospital and 392 unique families were referred to the program. The referred patients were representative of the communities in Massachusetts disproportionately affected by the COVID-19 pandemic. Furthermore, 79% of referred patients followed up with the initial referral, with sustained high participation rates throughout the program course; and they were provided with an average of four community resource referrals. Adoption and implementation of the key components in HUGS/Abrazos were found to be appropriate and acceptable. Furthermore, the implemented program remained consistent to the original design. Overall, HUGS/Abrazos was well adopted as an emergency relief program with strong post-COVID-19 applicability to ameliorate continuing toxic stressors while decreasing burden on the health system.

The Influence of Adverse Childhood Experiences (ACEs), Including the COVID-19 Pandemic, and Toxic Stress on Development and Health Outcomes of Latinx Children in the USA: a Review of the Literature.

The purpose of this review is to synthesize existing literature to analyze the influence of the Adverse Childhood Experiences (ACEs), including the COVID-19 pandemic, and toxic stress on child development and lifelong health outcomes of Latinx children in the USA, utilizing the ACE framework. Without adequate protective factors, children's early experiences with adversity and toxic stress have implications for their physiological, psychological, and social health. The COVID-19 pandemic has shown to exacerbate childhood adversity and toxic stress and has disproportionately harmed Latinx communities. In applying the ACE framework to US-Latinx populations, relevant findings concerning a potential failure of ACEs to accurately capture Latinx experiences of adversity were highlighted, as well as the need to classify the COVID-19 pandemic as an ACE. Research suggest that first-generation Latinx immigrants report lower-than-average rates of ACEs despite the various disparities ethnic minorities face in the USA. A discussion on whether this health paradox arises because of the failure of ACEs to properly identify adverse experiences unique to immigrants or if it is related with immigrant families' protective cultural factors. The compounding experiences of discrimination, immigration anxieties, and now also pandemic-related hardship that have the potential to harm Latinx children's cognitive, emotional, and physical development were highlighted. Evidence-based interventions that were discussed in this report include promotion of resiliency through healthy adult relationships, policies that screen for ACEs early on in a child's life, trauma-informed care and innovative treatment programs, and strengthening existing protective services through financial and political support.

Screening for Toxic Stress Response and Buffering Factors: A Case-Based, Trauma-Informed Approach to Health Equity.

Introduction: Exposure to adverse childhood experiences (ACEs) can lead to a toxic stress response with impacts on health that affect health equity. As part of our Health Equity, Social Justice, and Anti-racism curriculum, our aim was to introduce second-year medical students to a case-based method using a template-based screening and application of toxic stress, buffering factors, and resiliency-fostering tools to address health disparities and inequities with a trauma-informed care approach. Methods: We developed an asynchronous e-learning module that demonstrated the impact of ACEs by introducing students to screening for toxic stress response and buffering factors on health, their role as health equity determinants, and the use of brief in-clinic resilience-fostering tools in patient care. This was followed by a synchronous, facilitated, small-group, virtual discussion of a clinical case. Pre- and postworkshop surveys assessed changes in knowledge, skills, and attitudes. A 3-month follow-up survey assessed students' behavioral changes. Results: Sixty-four students completed the learning module. Paired t-test analysis showed a statistically significant increase in students' knowledge, skills, and attitudes regarding the Educational Objectives, with a survey response rate of 98%. Three months after the workshop, a third of students were applying these concepts, with a survey response rate of 87%. Discussion: Implementing this case-based curriculum in trauma-informed patient care helped increase opportunities for equitable health in patient encounters by providing students with the skills to screen for toxic stress, buffering, and brief in-clinic resiliency-fostering tools. Such skills will become even more impactful as we emerge from the COVID-19 pandemic.

How California became ACEs aware: A case study examining program implementation during the COVID-19 pandemic

The ACEs Aware initiative has positioned California as the first state to formally address childhood adversity and toxic stress as a public health crisis. Beginning January 2020, ACEs Aware offered training to healthcare providers and allocated Medi-Cal funds to reimburse providers that screen patients for adverse childhood experiences (ACEs). Prolonged exposure to trauma as a child can have a detrimental effect on an individual's development and overall well-being. The landmark ACE Study conducted by Kaiser Permanente and the Centers for Disease Control and Prevention in the late 1990's paved the way for clinical and community discussions about how to identify and address toxic stress in children and adolescents. Over 20 years later, state leadership in California, led by the Office of the Surgeon General, has set a goal to reduce ACEs and toxic stress by half in one generation. Through key informant interviews (n=31), this qualitative case study explores the implementation challenges and barriers that the ACEs Aware initiative navigated. Furthermore, this initiative launched just months before a global health crisis prompted the initiative to make adaptations in response to the societal impacts and increased stressors from the COVID-19 pandemic. Thematic analysis was used to identify themes across participant interviews to better understand the challenges that providers and community health leaders faced, how the goals and future directions of the initiative were impacted, and what lessons were learned that other states could build upon if they were to create a similar trauma-focused initiative. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

A Schema of Toxic Stress Informed by Racism, Transgenerational Stress, and Disadvantage.

INTRODUCTION: The Toxic Stress Schema (TSS) is an ecological framework with a social justice lens for identifying and alleviating stress and strengthening social determinants of health for children and families of color impacted by the COVID-19 pandemic and the cumulative effects of racism and generational, systemic inequities. METHOD: Relevant literature is reviewed, and examples were provided to illustrate the differential impacts of the "stress superstorm" of 2020 had on children of color based on their family's position on the advantage-disadvantage continuum. RESULTS: The utility of the TSS framework as a model for advanced nursing practice is demonstrated, and recommendations are formulated for the pediatric nurse practitioner's role in health policy. DISCUSSION: The COVID-19 pandemic elucidated the historical inequities experienced by children and families of color. The TSS framework provides a model for recognizing, organizing, and implementing.

The potential impact of the COVID-19 pandemic on child growth and development: a systematic review.

OBJECTIVE: This was a systematic review of studies that examined the impact of epidemics or social restriction on mental and developmental health in parents and children/adolescents. SOURCE OF DATA: The PubMed, WHO COVID-19, and SciELO databases were searched on March 15, 2020, and on April 25, 2020, filtering for children (0-18 years) and humans. SYNTHESIS OF DATA: The tools used to mitigate the threat of a pandemic such as COVID-19 may very well threaten child growth and development. These tools - such as social restrictions, shutdowns, and school closures - contribute to stress in parents and children and can become risk factors that threaten child growth and development and may compromise the Sustainable Development Goals. The studies reviewed suggest that epidemics can lead to high levels of stress in parents and children, which begin with concerns about children becoming infected. These studies describe several potential mental and emotional consequences of epidemics such as COVID-19, H1N1, AIDS, and Ebola: severe anxiety or depression among parents and acute stress disorder, post-traumatic stress, anxiety disorders, and depression among children. These data can be related to adverse childhood experiences and elevated risk of toxic stress. The more adverse experiences, the greater the risk of developmental delays and health problems in adulthood, such as cognitive impairment, substance abuse, depression, and non-communicable diseases. CONCLUSION: Information about the impact of epidemics on parents and children is relevant to policy makers to aid them in developing strategies to help families cope with epidemic/pandemic-driven adversity and ensure their children's healthy development.

Fostering Resilience in Pregnancy and Early Childhood During the COVID-19 Pandemic: The HUGS/Abrazos Program Design and Implementation.

Pregnancy and early childhood pose unique sensitivity to stressors such as economic instability, poor mental health, and social inequities all of which have been magnified by the COVID-19 pandemic. In absence of protective buffers, prolonged exposure to excessive, early adversity can lead to poor health outcomes with significant impact lasting beyond the childhood years. Helping Us Grow Stronger (HUGS/Abrazos) is a community-based program, designed and launched at the time of the COVID-19 surge in the Spring of 2020, that combines emergency relief, patient navigation, and direct behavioral health support to foster family resilience and mitigate the negative impacts of COVID-related toxic stress on pregnant women and families with children under age 6. Through a targeted referral process, community health workers provide resource navigation for social needs, and a social worker provides behavioral health support. The use of innovative tools such as a centralized resource repository, community health workers with specialized knowledge in this age range, and a direct referral system seeks to assist in streamlining communication and ensuring delivery of quality care. We aim to serve over 300 families within the 1st year. The HUGS/Abrazos program aims to fill an important void by providing the necessary tools and interventions to support pregnant women and young families impacted by adversity exacerbated by the COVID-19 pandemic.

Guardians at the Gate: Early Adversity, Neurocognitive Development, and the Role of the Pediatrician in the Era of COVID-19.

Adverse childhood experiences (ACEs) profoundly impact neurocognitive development. Specifically, when these events occur during critical periods of brain plasticity, a time of significant synaptogenesis, neural pruning, and myelination, typical neurodevelopment can become derailed. Adverse childhood experiences promote morphological changes in neuronal microcircuitry which may lead to diminished cognitive flexibility, inattention, increased impulsivity, decreased school readiness, and disruptive behaviors. In this regard, the current COVID-19 pandemic represents an especially complex adverse experience that disturbs a child's social milieu and support network, likely interfering with brain maturation and executive function. Here, we take a neurodevelopmental approach to argue for the critical role that pediatricians must fulfill in mitigating the potentially detrimental consequences of COVID-19. We call for ACE screening and anticipatory guidance in the primary care setting, and the use of validated interventions and skills to bolster resilience, when ACEs are identified. We present a clinical workflow for the physician to proactively assess, identify, stratify, and address the severity of ACEs worsened by COVID-19. We discuss home-based activities and resources for children and adolescents to promote stress reduction, connectiveness, and self-awareness and create a more positive environment to maximize neurodevelopmental potential in the face of the ongoing pandemic.

Supporting children and youth during the COVID-19 pandemic and beyond: A rights-centred approach.

The COVID-19 pandemic is an unprecedented global crisis, affecting millions globally and in Canada. While efforts to limit the spread of the infection and 'flatten the curve' may buffer children and youth from acute illness, these public health measures may worsen existing inequities for those living on the margins of society. In this commentary, we highlight current and potential long-term impacts of COVID-19 on children and youth centring on the UN Convention of the Rights of the Child (UNCRC), with special attention to the accumulated toxic stress for those in difficult social circumstances. By taking responsive action, providers can promote optimal child and youth health and well-being, now and in the future, through adopting social history screening, flexible care models, a child/youth-centred approach to "essential" services, and continual advocacy for the rights of children and youth.